Article
Variant sublines of early-stage human melanomas selected for tumorigenicity in nude mice express a multicytokine-resistant phenotype.
The American journal of pathology - 1 Apr 1994
Kobayashi H, Man S, MacDougall J R, Graham C H, Lu C, Kerbel R S
Abstract excerpt
Surgical removal of early-stage radial growth phase or vertical growth phase primary cutaneous human melanomas usually results in cure of the disease. Hence there are few examples of genetically-related paired human melanoma cell lines for study in which one member of the pair is from a curable e...
Topics
- Animals
- Blotting, Southern
- Collagen
- Cytokines
- DNA
- DNA Fingerprinting
- DNA Replication
- Drug Combinations
- Drug Resistance
- Female
- Humans
- Laminin
- Melanoma
- Mice
- Mice, Nude
- Phenotype
- Proteoglycans
- Skin Neoplasms