Development of a Stromal Microenvironment Experimental Model Containing Proto-Myofibroblast Like Cells and Analysis of Its Crosstalk with Melanoma Cells: A New Tool to Potentiate and Stabilize Tumor Suppressor Phenotype of Dermal Myofibroblasts.

doi:10.3390/cells8111435

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Development of a Stromal Microenvironment Experimental Model Containing Proto-Myofibroblast Like Cells and Analysis of Its Crosstalk with Melanoma Cells: A New Tool to Potentiate and Stabilize Tumor Suppressor Phenotype of Dermal Myofibroblasts.

Cells - 14 Nov 2019

Avagliano Angelica, Ruocco Maria Rosaria, Nasso Rosarita, Aliotta Federica, Sanità Gennaro, Iaccarino Antonino, Bellevicine Claudio, Calì Gaetano, Fiume Giuseppe, Masone Stefania, Masullo Mariorosario, Montagnani Stefania, Arcucci Alessandro

Abstract excerpt

Melanoma is one of the most aggressive solid tumors and includes a stromal microenvironment that regulates cancer growth and progression. The components of stromal microenvironment such as fibroblasts, fibroblast aggregates and cancer-associated fibroblasts (CAFs) can differently influence the melanoma growth during its distinct stages. In this work, we have developed and studied a stromal microenvironment model,...

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PMID: 31739477
DOI: 10.3390/cells8111435
PMCID: PMC6912587

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Development of a Stromal Microenvironment Experimental Model Containing Proto-Myofibroblast Like Cells and Analysis of Its Crosstalk with Melanoma Cells: A New Tool to Potentiate and Stabilize Tumor Suppressor Phenotype of Dermal Myofibroblasts.PMID 31739477Read ↗

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