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Article

Detection of reactivation and size variation in the regulatory region of JC virus in brain tissue.

Journal of clinical pathology - 1 Jul 1993

Mehal W Z, Esiri M M, Lo Y M, Chapman R W, Fleming K A

Abstract excerpt

AIMS: To develop a sensitive and specific polymerase chain reaction (PCR) based system for detecting genomic variation in JC virus. To apply this system to formalin fixed, paraffin wax embedded brain tissue from patients with and without progressive multifocal leucoencephalopathy (PML). METHODS: A pair of primers (JC1 and JC2) were designed to be complementary to the early and late regions of JC and BK...

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Identifiers

PMID: 8157753
DOI: 10.1136/jcp.46.7.646
PMCID: PMC501395

Genes

PML

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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