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Article

Allelic polymorphism in the coding region of human TCR C alpha gene and characterization of structural variability in the alpha chain constant domain.

International immunology - 1 Feb 1994

Bragado R, García A, Treviño M A, Vilches C, López de Castro J A

Abstract excerpt

An allelic variant of the human TCR C alpha gene, designated C alpha AL, which encodes a structurally different protein product has been characterized. C alpha AL was independently sequenced using polymerase chain reaction (PCR)-amplified TCR C alpha cDNA from various T cell clones derived from a same individual. It differed from the most usual C alpha sequence by two non-synonymous base changes at codons 4...

Topics

Alleles
Base Sequence
Clone Cells
Humans
Molecular Sequence Data
Polymerase Chain Reaction
Polymorphism, Genetic
Receptors, Antigen, T-Cell, alpha-beta
Spain

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 8155598
DOI: 10.1093/intimm/6.2.223

Genes

GAA
GCA

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-8155598-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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