Article
Early cardiac development: a view from stem cells to embryos.
Cardiovascular research - 1 Dec 2012
Van Vliet Patrick, Wu Sean M, Zaffran Stéphane, Pucéat Michel
Abstract excerpt
From the 1920s, early cardiac development has been studied in chick and, later, in mouse embryos in order to understand the first cell fate decisions that drive specification and determination of the endocardium, myocardium, and epicardium. More recently, mouse and human embryonic stem cells (ESCs) have demonstrated faithful recapitulation of early cardiogenesis and have contributed significantly to this research...
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