Structure and heterogeneity of the a sequences of human herpesvirus 6 strain variants U1102 and Z29 and identification of human telomeric repeat sequences at the genomic termini.

Abstract excerpt

The unit-length genome of human herpesvirus 6 (HHV-6) consists of a single unique component (U) bounded by direct repeats DRL and DRR and forms head-to-tail concatemers during productive infection. cis-elements which mediate cleavage and packaging of progeny virions (a sequences) are found at the termini of all herpesvirus genomes. In HHV-6, DRL and DRR are identical and a sequences may therefore also occur at...

Topics

• Base Sequence
• DNA, Viral
• Genetic Variation
• Genome, Viral
• Herpesvirus 6, Human
• Humans
• Molecular Sequence Data
• Nucleic Acid Conformation
• Repetitive Sequences, Nucleic Acid
• Sequence Homology, Nucleic Acid