Article
A mouse B16 melanoma mutant deficient in glycolipids.
Proceedings of the National Academy of Sciences of the United States of America - 29 Mar 1994
Ichikawa S, Nakajo N, Sakiyama H, Hirabayashi Y
Abstract excerpt
Mouse B16 melanoma cell line, GM-95 (formerly designated as MEC-4), deficient in sialyllactosylceramide was examined for its primary defect. Glycolipids from the mutant cells were analyzed by high-performance TLC. No glycolipid was detected in GM-95 cells, even when total lipid from 10(7) cells w...
Topics
- Animals
- Cell Division
- Culture Media, Serum-Free
- Fluorescent Antibody Technique
- G(M3) Ganglioside
- Glucosyltransferases
- Lectins
- Lipids
- Melanoma, Experimental
- Mice
- Mutation