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Article

Mutant alleles of tRNA(Thr) genes suppress the hisG46 missense mutation in Salmonella typhimurium.

Environmental and molecular mutagenesis - 1 Jan 1994

Kupchella E, Koch W H, Cebula T A

Abstract excerpt

Extragenic suppressors of the hisG46 missense mutation were mapped to the 71 and 88 min regions of the Salmonella typhimurium chromosome, positions that in Escherichia coli contain the thrV (tRNA(Thr1)) and thrT (tRNA(Thr3)) genes, respectively. The suppressor loci were identified as mutant alleles of thrV and thrT, using allele-specific colony hybridization. An oligomer, based on the conserved 5' sequence of the...

Topics

Alleles
Analysis of Variance
Anticodon
Base Sequence
Chromosome Mapping
Conserved Sequence
DNA, Bacterial
Genes, Suppressor
Histidine
Molecular Sequence Data
Mutagenicity Tests

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Plasmids

RNA, Transfer, Thr

Salmonella typhimurium

Transduction, Genetic

Source

Identifiers

PMID: 8143705
DOI: 10.1002/em.2850230202

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-8143705-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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