Phenotypic suppression of DNA gyrase deficiencies by a deletion lowering the gene dosage of a major tRNA in Salmonella typhimurium.

doi:10.1128/jb.176.8.2216-2226.1994

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Article

Phenotypic suppression of DNA gyrase deficiencies by a deletion lowering the gene dosage of a major tRNA in Salmonella typhimurium.

Journal of bacteriology - 1 Apr 1994

Blanc-Potard A B, Bossi L

Abstract excerpt

One of the pleiotropic phenotypes of mutations affecting DNA gyrase activity in Salmonella typhimurium is the constitutive deattenuation of the histidine operon. In the present work, we isolated and characterized a suppressor mutation which restores his attenuation in the presence of a defective...

Topics

Base Sequence
DNA Topoisomerases, Type II
Gene Deletion
Genes, Bacterial
Genes, Suppressor
Histidine
Molecular Sequence Data
Mutation
Nalidixic Acid
Phenotype
RNA, Bacterial
RNA, Transfer, Arg
Salmonella typhimurium

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