Article
Measurement of chromosomal aberrations, sister chromatid exchange, hprt mutations, and DNA adducts in peripheral lymphocytes of human populations at increased risk for cancer.
Environmental health perspectives - 1 Oct 1993
Jacobson-Kram D, Albertini R J, Branda R F, Falta M T, Iype P T, Kolodner K, Liou S H, McDiarmid M A, Morris M, Nicklas J A
Abstract excerpt
Using a multidisciplinary approach, we have measured various indicators of DNA damage in peripheral lymphocytes of human populations potentially at increased risk for cancer. Sister chromatid exchanges (SCE) and polycyclic aromatic hydrocarbon (PAH)-DNA adducts were evaluated in a group of firefi...
Topics
- Chromosome Aberrations
- DNA
- Humans
- Lymphocytes
- Male
- Mutation
- Neoplasms
- Occupational Exposure
- Risk Factors
- Sister Chromatid Exchange