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Assessment of primary, oxidative and excision repaired DNA damage in hospital personnel handling antineoplastic drugs.

Mutagenesis - 1 May 2011

Villarini Milena, Dominici Luca, Piccinini Renza, Fatigoni Cristina, Ambrogi Maura, Curti Gianluca, Morucci Piero, Muzi Giacomo, Monarca Silvano, Moretti Massimo

Abstract excerpt

The International Agency for Research on Cancer has classified several antineoplastic drugs in Group 1 (human carcinogens), among which chlorambucil, cyclophosphamide (CP) and tamoxifen, Group 2A (probable human carcinogens), among which cisplatin, etoposide, N-ethyl- and N-methyl-N-nitrosourea, and Group 2B (possible human carcinogens), among which bleomycins, merphalan and mitomycin C. The widespread use of...

Topics

Antineoplastic Agents
Cancer Care Facilities
Comet Assay
Cytarabine
DNA Damage
Fluorouracil
Genotype
Glutathione S-Transferase pi
Glutathione Transferase
Humans

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Italy

Nursing Staff, Hospital

Occupational Exposure

Polymorphism, Restriction Fragment Length

Regression Analysis

Statistics, Nonparametric

Tumor Suppressor Protein p53

Source

Identifiers

PMID: 21112930
DOI: 10.1093/mutage/geq102

Genes

GSTM1
GSTP1
GSTT1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026.

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