Article
An individual with a high prevalence of a tat-defective provirus in peripheral blood.
AIDS research and human retroviruses - 1 Dec 1993
Sabino E, Cheng-Mayer C, Mayer A
Abstract excerpt
The first exon of tat was sequenced from 23 provirus genomes randomly amplified directly from an HIV-1-infected individual's peripheral blood. Twelve of the 23 sequences constituted a distinct subset of the quasi-species detected. This subset had in common two inactivating mutations in the tat gene. In addition, two of these defective genomes each had a unique mutation. This is the second instance of a defective...
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