Article
An individual with a high prevalence of a tat-defective provirus in peripheral blood.
AIDS research and human retroviruses - 1 Dec 1993
Sabino E, Cheng-Mayer C, Mayer A
Abstract excerpt
The first exon of tat was sequenced from 23 provirus genomes randomly amplified directly from an HIV-1-infected individual's peripheral blood. Twelve of the 23 sequences constituted a distinct subset of the quasi-species detected. This subset had in common two inactivating mutations in the tat ge...
Topics
- Base Sequence
- DNA Primers
- DNA, Viral
- Defective Viruses
- Genes, tat
- Genome, Viral
- HIV Infections
- HIV-1
- Humans
- Molecular Sequence Data
- Mutation
- Polymerase Chain Reaction
- Proviruses