Article
Evaluation of quantitative variation in gene expression.
Nucleic acids research - 11 Mar 1994
Spanakis E, Brouty-Boyé D
Abstract excerpt
We investigate the behaviour of the gene-expression rate as a statistical variable using autoradiographic data for 39 transcripts from a heterogeneous set of 80 breast-tissue cultures. Despite standardization, the data distributions of all transcripts showed intervals of normality and intervals of systematic departure from normality which most frequently resulted in a significant skewness and/or kurtosis....
Topics
- Animals
- Breast Neoplasms
- Gene Expression Regulation, Neoplastic
- Genetic Variation
- Humans
- Matrix Metalloproteinase 11
- Metalloendopeptidases
- Receptors, Somatomedin
- Signal Transduction
- Tumor Cells, Cultured