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Article

Overexpression of C-terminally but not N-terminally truncated Myb induces fibrosarcomas: a novel nonhematopoietic target cell for the myb oncogene.

Molecular and cellular biology - 1 Apr 1994

Press R D, Reddy E P, Ewert D L

Abstract excerpt

The myb oncogene encodes a DNA-binding transcriptional transactivator which can become a hematopoietic cell-transforming protein following the deletion of amino acid sequences from either its amino or carboxyl terminus. Although a number of hematopoietic tumors express terminally deleted variants of Myb, the involvement of truncated Myb in nonhematopoietic tumors has not been adequately investigated. To assess...

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Identifiers

PMID: 8139533
DOI: 10.1128/mcb.14.4.2278-2290.1994
PMCID: PMC358594

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Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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Research trail→

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Overexpression of C-terminally but not N-terminally truncated Myb induces fibrosarcomas: a novel nonhematopoietic target cell for the myb oncogene.PMID 8139533Read ↗

Functional genomic analysis reveals distinct neoplastic phenotypes associated with c-myb mutation in the bursa of Fabricius.Semantic proximity Read ↗

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Transcriptional regulation by the carboxyl terminus of c-Myb depends upon both the Myb DNA-binding domain and the DNA recognition site.Semantic proximity Read ↗

Homodimerization of the Meq Viral Oncoprotein Is Necessary for Induction of T-Cell Lymphoma by Marek's Disease VirusSemantic proximity Read ↗

Myb drives B-cell neoplasms and myeloid malignancies in vivoSemantic proximity Read ↗

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Mutations within the 5' half of the avian retrovirus MC29 v-myc gene alter or abolish transformation of chicken embryo fibroblasts and macrophages.Semantic proximity Read ↗

c-Myb and v-Myb are differentially phosphorylated by p42mapk in vitro.Semantic proximity Read ↗

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