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Article

Retroviral insertional activation of the c-myb proto-oncogene in a Marek's disease T-lymphoma cell line.

Journal of virology - 1 Nov 1996

Le Rouzic E, Perbal B

Abstract excerpt

Marek's disease virus (MDV) is an avian herpesvirus that causes, in chickens, a lymphoproliferative disease characterized by malignant transformation of T lymphocytes. The rapid onset of polyclonal tumors indicates the existence of MDV-encoded oncogenic products. However, the molecular basis of MDV-induced lymphoproliferative disease and latency remains largely unclear. Several lines of evidence suggest that MDV...

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Identifiers

PMID: 8892859
DOI: 10.1128/JVI.70.11.7414-7423.1996
PMCID: PMC190808

Genes

MYB

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Retroviral insertional activation of the c-myb proto-oncogene in a Marek's disease T-lymphoma cell line.PMID 8892859Read ↗

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Marek's disease virus Meq transforms chicken cells via the v-Jun transcriptional cascade: A converging transforming pathway for avian oncovirusesSemantic proximity Read ↗

Homodimerization of Marek's Disease Virus-Encoded Meq Protein Is Not Sufficient for Transformation of Lymphocytes in ChickensSemantic proximity Read ↗

MicroRNA Profile of Marek's Disease Virus-Transformed T-Cell Line MSB-1: Predominance of Virus-Encoded MicroRNAsSemantic proximity Read ↗

Expression profiles of microRNAs encoded by the oncogenic Marek's disease virus reveal two distinct expression patterns in vivo during different phases of diseaseSemantic proximity Read ↗

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