Article
Retroviral insertional activation of the c-myb proto-oncogene in a Marek's disease T-lymphoma cell line.
Journal of virology - 1 Nov 1996
Le Rouzic E, Perbal B
Abstract excerpt
Marek's disease virus (MDV) is an avian herpesvirus that causes, in chickens, a lymphoproliferative disease characterized by malignant transformation of T lymphocytes. The rapid onset of polyclonal tumors indicates the existence of MDV-encoded oncogenic products. However, the molecular basis of M...
Topics
- Alleles
- Avian Leukosis Virus
- DNA, Viral
- Deoxyribonuclease BamHI
- Gene Expression
- Gene Rearrangement
- Herpesvirus 2, Gallid
- Lymphoma, T-Cell
- Proto-Oncogene Proteins
- Proto-Oncogene Proteins c-myb
- RNA, Messenger
- Trans-Activators
