Article
High-resolution HLA-DPB typing based upon computerized analysis of data obtained by fluorescent sequencing of the amplified polymorphic exon 2.
Human immunology - 1 Dec 1993
Versluis L F, Rozemuller E, Tonks S, Marsh S G, Bouwens A G, Bodmer J G, Tilanus M G
Abstract excerpt
To differentiate 32 HLA-DPB alleles, conventional techniques such as serology and cellular typing are inadequate for high-resolution DPB typing. The most refined DNA typing until now is SSO typing and new selected oligonucleotides can be added to this system to distinguish new allele sequences. DNA sequencing, however, reveals directly the sequence information of all polymorphic HVRs and has the advantage of...
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