Novel association approach for determining the genetic predisposition to schizophrenia: case-control resource and testing of a candidate gene.

doi:10.1002/ajmg.1320480108

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Article

Novel association approach for determining the genetic predisposition to schizophrenia: case-control resource and testing of a candidate gene.

American journal of medical genetics - 1 May 1993

Sobell J L, Heston L L, Sommer S S

Abstract excerpt

We have developed a two-tiered approach to elucidating the genetic predisposition to schizophrenia. The approach first involves the examination of candidate genes in a subset of schizophrenic individuals to identify DNA sequence variations of likely functional significance, i.e., that produce eit...

Topics

Adult
Age Factors
Alleles
Base Sequence
Case-Control Studies
Chi-Square Distribution
DNA
Female
Genetic Linkage
Genetic Variation
Heterozygote
Humans

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Male

Middle Aged

Molecular Sequence Data

Mutation

Oligodeoxyribonucleotides

Phenylalanine Hydroxylase

Source

Open in PubMed

Identifiers

PMID: 8357034
DOI: 10.1002/ajmg.1320480108

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-8357034-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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