Strong intra-species variability in the metabolic conversion of six procarcinogens to somatic cell recombinagens in Drosophila.

doi:10.1093/mutage/8.6.543

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Article

Strong intra-species variability in the metabolic conversion of six procarcinogens to somatic cell recombinagens in Drosophila.

Mutagenesis - 1 Nov 1993

Rodriguez-Arnaiz R, Vogel E W, Szakmary A

Abstract excerpt

Genetic heterogeneity in response to genotoxic carcinogens requiring metabolic conversion has been studied in Drosophila, using seven different genotypes in combination with the w/w+ eye mosaic assay for mitotic recombination. The set of tester strains examined consisted of four wild-type laborat...

Topics

Animals
Biotransformation
Carcinogenicity Tests
Carcinogens
Drosophila melanogaster
Eye Color
Genetic Variation
Genotype
Larva
Methyl Methanesulfonate
Mosaicism
Polycyclic Compounds
Prodrugs
Species Specificity
Vinyl Compounds

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