Article
Genetic activities of 4-chloromethylbiphenyl, the 4-hydroxy derivative and benzyl chloride in the soma and germ line of Drosophila melanogaster.
Mutation research - 1 Jan 2000
Fahmy M J, Fahmy O G
Abstract excerpt
The genetic activities of 4CMB, 4HMB and BC were assayed as regards the induction of somatic alterations in gene expression on an unstable w+ locus with an intragenic TE and all the simultaneously induced germinal mutations on the X-chromosome carrying this locus. The compounds were applied topically in solution at equimolar doses on late embryos and newly hatched larvae. The somatic events were scored as...
Topics
- Animals
- Benzyl Compounds
- Biphenyl Compounds
- Drosophila melanogaster
- Embryo, Nonmammalian
- Female
- Larva
- Male
- Mutagenicity Tests
- Mutagens
- Mutation
- X Chromosome
