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Article

Host-inhibitory functions encoded by promiscuous plasmids. Transient arrest of Escherichia coli segregants that fail to inherit plasmid RK2.

Journal of molecular biology - 18 Mar 1994

Jovanovic O S, Ayres E K, Figurski D H

Abstract excerpt

An effective strategy for a plasmid to be maintained in a growing population of bacteria is to prevent the proliferation of newly formed daughter cells that lack the plasmid. In this study, we determined that the promiscuous, incompatibility group P plasmid RK2 encodes such a system. To induce large numbers of RK2-free segregants of an RK2-containing host, we designed a genetic system that made RK2 replication...

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Identifiers

PMID: 8133520
DOI: 10.1006/jmbi.1994.1208

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