Article
Molecular basis for "null" lipoprotein(a) phenotypes and the influence of apolipoprotein(a) size on plasma lipoprotein(a) level in the baboon.
The Journal of biological chemistry - 25 Mar 1994
White A L, Hixson J E, Rainwater D L, Lanford R E
Abstract excerpt
High plasma levels of lipoprotein(a) (Lp(a)) and its unique apolipoprotein, apo(a), are an independent risk factor for cardiovascular disease. Plasma Lp(a) levels vary over a 1000-fold range and are determined by the apo(a) locus, which has at least 34 alleles expressing apo(a) isoforms with mole...
Topics
- Animals
- Apolipoproteins
- Apoprotein(a)
- Biological Transport
- Cell Compartmentation
- Endoplasmic Reticulum
- Gene Expression
- Lipoprotein(a)
- Molecular Weight
- Papio
- Phenotype
- Protein Processing, Post-Translational
- RNA, Messenger
