Article
lasA and lasB genes of Pseudomonas aeruginosa: analysis of transcription and gene product activity.
Infection and immunity - 1 Apr 1994
Toder D S, Ferrell S J, Nezezon J L, Rust L, Iglewski B H
Abstract excerpt
The lasA gene was the first of the Pseudomonas aeruginosa genes involved in proteolysis and elastolysis to be cloned and sequenced. Its function and significance have been studied by genetic approaches (D. S. Toder, M. J. Gambello, and B. H. Iglewski, Mol. Microbiol. 5:2003-2010, 1991) and by attempts to purify an active fragment of the protein (J. E. Peters and D. R. Galloway, J. Bacteriol. 172:2236-2240, 1990)....
Topics
- Bacterial Proteins
- Genes, Bacterial
- Genetic Complementation Test
- Metalloendopeptidases
- Mutation
- Pancreatic Elastase
- Promoter Regions, Genetic
- Pseudomonas aeruginosa
- Transcription, Genetic