Article
Finding noncommunicating sets for Markov chain Monte Carlo estimations on pedigrees.
American journal of human genetics - 1 Apr 1994
Lin S, Thompson E, Wijsman E
Abstract excerpt
Markov chain Monte Carlo (MCMC) has recently gained use as a method of estimating required probability and likelihood functions in pedigree analysis, when exact computation is impractical. However, when a multiallelic locus is involved, irreducibility of the constructed Markov chain, an essential requirement of the MCMC method, may fail. Solutions proposed by several researchers, which do not identify all the...
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