Achieving irreducibility of the Markov chain Monte Carlo method applied to pedigree data.

doi:10.1093/imammb/10.1.1

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Article

Achieving irreducibility of the Markov chain Monte Carlo method applied to pedigree data.

IMA journal of mathematics applied in medicine and biology - 1 Jan 1993

Lin S, Thompson E, Wijsman E

Abstract excerpt

Markov chain Monte Carlo (MCMC) methods have been explored by various researchers as an alternative to exact probability computation in statistical genetics. The objective is to simulate a Markov chain with the desired equilibrium distribution. If the transition kernel is aperiodic and irreducibl...

Topics

Algorithms
Alleles
Analysis of Variance
Biometry
Female
Genetics, Medical
Genotype
Humans
Likelihood Functions
Male
Markov Chains
Monte Carlo Method
Pedigree
Probability

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