Article
Monoclonal antibody, LR-2, recognizes an immunoglobulin-linked signaling molecule on murine B cells.
Cellular immunology - 1 Feb 1994
Marshall-Clarke S, Greenwood M
Abstract excerpt
The studies presented here examine the effect of a monoclonal rat antibody, LR-2, on the proliferation of growth-inhibitable murine B lymphoma lines. Like anti-immunoglobulin, mAb LR-2 is capable of inducing growth arrest in these cells, implying that ligation of the LR-2 cell surface molecule by...
Topics
- Animals
- Antibodies, Monoclonal
- B-Lymphocytes
- Cell Differentiation
- Cell Division
- Lymphocyte Activation
- Lymphoma, B-Cell
- Mice
- Mutation
- Rats
- Receptors, Antigen, B-Cell
- Receptors, Immunologic
- Signal Transduction
- Tumor Cells, Cultured