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Article

[Molecular pathology of colorectal cancer].

Revue medicale de la Suisse romande - 1 Oct 1999

Bosman F T, Joris F

Abstract excerpt

The identification of several types of familial colorectal cancer has led to the discovery of some of the genes involved in these diseases. It was subsequently shown that somatic mutations of these genes (APC, mismatch repair genes, TP53) also occur in sporadic colorectal cancer. Gradually, this molecular information is being incorporated into the standard histopathological analysis of colorectal cancer and can...

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PMID: 10582488

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APC

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