Article
A screen for yeast mutants with defects in the dolichol-mediated pathway for N-glycosylation.
Proceedings of the National Academy of Sciences of the United States of America - 15 Feb 1994
Roos J, Sternglanz R, Lennarz W J
Abstract excerpt
Dolichol in the form of dolichyl phosphate participates in the synthesis of N- and O-linked glycoproteins and phosphatidylinositol-linked proteins in the yeast Saccharomyces cerevisiae. In this organism, as well as in higher eukaryotes, a number of the enzymes in the polyisoprenoid and glycoprote...
Topics
- Amino Acid Sequence
- Carbohydrate Sequence
- Cloning, Molecular
- Dolichol Phosphates
- Genes, Fungal
- Genetic Complementation Test
- Glycopeptides
- Glycosylation
- Hexosyltransferases
- Membrane Proteins
- Molecular Sequence Data
- Mutation
- Oligosaccharides
- Saccharomyces cerevisiae
- Transferases