Article
Glycoprotein biosynthesis in Saccharomyces cerevisiae: ngd29, an N-glycosylation mutant allelic to och1 having a defect in the initiation of outer chain formation.
FEBS letters - 14 Aug 1995
Lehle L, Eiden A, Lehnert K, Haselbeck A, Kopetzki E
Abstract excerpt
Outer chain glycosylation in Saccharomyces cerevisiae leads to heterogeneous and immunogenic asparagine-linked saccharide chains containing more than 50 mannose residues on secreted glycoproteins. Using a [3H]mannose suicide selection procedure a collection of N-glycosylation defective mutants (d...
Topics
- Alleles
- Animals
- Asparagine
- Carbohydrate Sequence
- Fungal Proteins
- Genes, Fungal
- Glucose Oxidase
- Glycoside Hydrolases
- Glycosylation
- Mammals
- Mannosyltransferases
- Membrane Glycoproteins
- Molecular Sequence Data
- Mutation
- Oligosaccharides
- Open Reading Frames
- Restriction Mapping
- Saccharomyces cerevisiae