Article
Glioblastoma growth inhibited in vivo by a dominant-negative Flk-1 mutant.
Nature - 10 Feb 1994
Millauer B, Shawver L K, Plate K H, Risau W, Ullrich A
Abstract excerpt
Angiogenesis, the sprouting of capillaries from pre-existing blood vessels, is a fundamental process in the formation of the vascular system during embryonic development. In adulthood, angiogenesis takes place during corpus luteum formation and in pathological conditions such as wound healing, diabetic retinopathy, and tumor-igenesis. Vascularization is essential for solid tumour growth and is thought to be...
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