Article
Functional analysis of N-linked glycosylation mutants of the measles virus fusion protein synthesized by recombinant vaccinia virus vectors.
Journal of virology - 1 Mar 1994
Alkhatib G, Shen S H, Briedis D, Richardson C, Massie B, Weinberg R, Smith D, Taylor J, Paoletti E, Roder J
Abstract excerpt
The role of N-linked glycosylation in the biological activity of the measles virus (MV) fusion (F) protein was analyzed by expressing glycosylation mutants with recombinant vaccinia virus vectors. There are three potential N-linked glycosylation sites located on the F2 subunit polypeptide of MV F, at asparagine residues 29, 61, and 67. Each of the three potential glycosylation sites was mutated separately as well...
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