Article
Role of basic residues in the proteolytic activation of Sendai virus fusion glycoprotein.
Virus research - 1 Apr 1995
Heminaway B R, Yang Y, Tanaka Y, Panin M, Huang Y T, Galinski M S
Abstract excerpt
Cleavage activation of the Sendai virus (Fushimi strain) fusion (F) protein was analyzed by site-directed mutagenesis of the amino acids proximal to the highly conserved fusion peptide. In addition, the functional properties of the wild-type and mutant proteins were examined to determine their ability to elicit the formation of syncytia when co-expressed with the hemagglutinin-neuraminidase (HN) glycoprotein....
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