Article
Carbohydrate modifications of the NDV fusion protein heptad repeat domains influence maturation and fusion activity.
Virology - 10 May 2001
McGinnes L, Sergel T, Reitter J, Morrison T
Abstract excerpt
The amino acid sequence of the fusion protein (F) of Newcastle disease virus (NDV) has six potential N-linked glycosylation addition sites, five in the ectodomain (at amino acids 85, 191, 366, 447, and 471) and one in the cytoplasmic domain at amino acid 542. Two of these sites, at positions 191 and 471, are within heptad repeat (HR) domains implicated in fusion activity of the protein. To determine glycosylation...
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