Article
Modification of radiation-induced damage by hyperthermia--role of repair processes.
International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group - 1 Jan 2000
Deorukhakar V V, Anjaria K B, Rao B S
Abstract excerpt
The role of repair inhibition in hyperthermic sensitization has been investigated by carrying out interaction studies (non-lethal heat plus radiation) using three radiosensitive mutant strains rad 9-4, rad 51, rad 52 of diploid yeast. The radiosensitization observed in these mutants is compared with that obtained in a wild type strain X2180. Stationary phase cells were heat treated at 51 degrees C for 30 min and...
Topics
- DNA Damage
- DNA Repair
- DNA, Fungal
- Hot Temperature
- Mutation
- Radiation Tolerance
- Saccharomyces cerevisiae
