Article
Role of RAD9-dependent cell-cycle checkpoints in the adaptive response to ionizing radiation in yeast, Saccharomyces cerevisiae.
International journal of radiation biology - 1 Sept 2000
Dolling J A, Boreham D R, Bahen M E, Mitchel R E
Abstract excerpt
PURPOSE: To determine whether yeast cells (Saccharomyces cerevisiae) defective in damage-inducible cell-cycle arrest can invoke an adaptive response and become resistant to normally lethal doses of ionizing radiation. MATERIALS AND METHODS: Wild-type yeast cells, cells defective for DNA-damage-responsive G1 and G2 cell-cycle arrest (rad9delta), and cells defective for recombinational repair of DNA damage (rad50,...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
