Article
Heterogeneity and stability characteristics of Candid 1 attenuated strain of Junin virus.
Acta virologica - 1 Feb 1993
Contigiani M, Medeot S, Diaz G
Abstract excerpt
Fourteen clones of Candid 1 strain of Junin virus were studied in terms of their attenuation and stability for 9 days-old mice. The cluster analysis of the efficiency of lethal infection, namely the virulence (lethality) indicates (PFU/LD50) of the clones showed that the strain population is heterogeneous. It is constituted by subpopulations with lower and higher virulence as compared to the parent strain....
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