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Article

Heterogeneity and stability characteristics of Candid 1 attenuated strain of Junin virus.

Acta virologica - 1 Feb 1993

Contigiani M, Medeot S, Diaz G

Abstract excerpt

Fourteen clones of Candid 1 strain of Junin virus were studied in terms of their attenuation and stability for 9 days-old mice. The cluster analysis of the efficiency of lethal infection, namely the virulence (lethality) indicates (PFU/LD50) of the clones showed that the strain population is heterogeneous. It is constituted by subpopulations with lower and higher virulence as compared to the parent strain....

Topics

Animals
Drug Stability
Genetic Variation
Guinea Pigs
Junin virus
Mice
Vaccines, Attenuated
Vero Cells
Viral Plaque Assay
Virulence

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 8105651

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-8105651-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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