Article
[Intracerebral infection of athymic mice with an attenuated strain of Junín virus].
Revista Argentina de microbiologia - 1 Jan 2000
Winocur D H, Videla C, Laguens R, Carballal G
Abstract excerpt
Infection of newborn immunocompetent (nu/+) mice with the XJ prototype strain of Junin virus, etiological agent of Argentine Hemorrhagic Fever, produces a lethal meningo-encephalitis due to cellular immune response. The same strain inoculated into athymic (nu/nu) mice produces an asymptomatic per...
Topics
- Animals
- Animals, Newborn
- Arenaviruses, New World
- Brain
- Disease Susceptibility
- Genetic Predisposition to Disease
- Immunity, Cellular
- Immunocompetence
- Lung
- Meningoencephalitis
- Mice
- Mice, Nude
- Pulmonary Fibrosis
- Viremia
