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[Intracerebral infection of athymic mice with an attenuated strain of Junín virus].

Revista Argentina de microbiologia - 1 Jan 2000

Winocur D H, Videla C, Laguens R, Carballal G

Abstract excerpt

Infection of newborn immunocompetent (nu/+) mice with the XJ prototype strain of Junin virus, etiological agent of Argentine Hemorrhagic Fever, produces a lethal meningo-encephalitis due to cellular immune response. The same strain inoculated into athymic (nu/nu) mice produces an asymptomatic persistent infection. The purpose of this work was to determine the nu/nu mice response when infected with XJCl3, an...

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PMID: 1966306

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