Article
Calomys musculinus, the natural reservoir of Argentine haemorrhagic fever, is a semipermissive host for a mouse-attenuated mutant of Junin virus.
Research in virology - 1 Jan 2000
Scolaro L A, Damonte E B
Abstract excerpt
C167, a mouse-attenuated strain of Junin virus derived from the XJC13 strain, also displayed reduced virulence for the South American cricetid Calomys musculinus, a natural reservoir of this virus in nature. Intracerebral inoculation of C. musculinus with 500 PFU of C167 produced only 25% mortality, whereas the parental XJC13 killed 85% of the animals. The attenuation of C167 for this cricetid was lower than for...
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