Calomys musculinus, the natural reservoir of Argentine haemorrhagic fever, is a semipermissive host for a mouse-attenuated mutant of Junin virus.

doi:10.1016/s0923-2516(07)80038-0

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Article

Calomys musculinus, the natural reservoir of Argentine haemorrhagic fever, is a semipermissive host for a mouse-attenuated mutant of Junin virus.

Research in virology - 1 Jan 2000

Scolaro L A, Damonte E B

Abstract excerpt

C167, a mouse-attenuated strain of Junin virus derived from the XJC13 strain, also displayed reduced virulence for the South American cricetid Calomys musculinus, a natural reservoir of this virus in nature. Intracerebral inoculation of C. musculinus with 500 PFU of C167 produced only 25% mortali...

Topics

Animals
Chlorocebus aethiops
Disease Reservoirs
Hemorrhagic Fever, American
Junin virus
Muridae
Mutation
Superinfection
Vero Cells
Virulence
Virus Replication

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