Article
[Phenotypic markers of attenuation in Junin virus strains recently isolated from individuals vaccinated with Junin Candid#1 strain].
Medicina - 1 Jan 2013
Gamboa Graciela S, Ambrosio Ana María, Maiza Andrea S, Mariani Mauricio, Rodrigues Garcia Armôa Geraldo, Saavedra María Del Carmen
Abstract excerpt
Argentine hemorrhagic fever is a severe acute disease caused by Junin virus. For prevention of this disease an effective vaccine called Candid#1 has been developed, composed of a live attenuated Junin virus strain. During a clinical trial conducted at Instituto Nacional de Enfermedades Virales Humanas (INEVH) in 2005, Junin virus was isolated from two vaccinated volunteers by co-culture of peripheral mononuclear...
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