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Article

Mutational trends in V3 loop protein sequences observed in different genetic lineages of human immunodeficiency virus type 1.

Journal of virology - 1 Oct 1994

Korber B T, MacInnes K, Smith R F, Myers G

Abstract excerpt

Highly variable international human immunodeficiency virus type 1 envelope sequences can be assigned to six major clades, or phylogenetically defined subtypes, designated A through F. These subtypes are approximately equidistant in terms of evolutionary distance measured by nucleotide sequences. This radiation from a common ancestral sequence may have been in step with the spread of the pandemic. In this study,...

Topics

Amino Acid Sequence
Consensus Sequence
Gene Products, env
Genes, env
Genetic Variation
HIV-1
Humans
Molecular Sequence Data
Mutation
Phylogeny

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Identifiers

PMID: 8084005
DOI: 10.1128/JVI.68.10.6730-6744.1994
PMCID: PMC237094

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-8084005-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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