Article
Genome scanning of human breast carcinomas using micro- and minisatellite core probes.
Genomics - 1 Jul 1993
Hovig E, Mullaart E, Børresen A L, Uitterlinden A G, Vijg J
Abstract excerpt
We have analyzed tumor and lymphocyte DNA from six breast cancer patients by one- and two-dimensional DNA fingerprinting using micro- and minisatellite core probes to estimate the extent and nature of DNA alterations in tumors. Both approaches were compared regarding sensitivity in genome analysi...
Topics
- Adult
- Alleles
- Base Sequence
- Breast Neoplasms
- Carcinoma, Ductal, Breast
- Chromosome Deletion
- DNA Fingerprinting
- DNA Probes
- DNA, Neoplasm
- DNA, Satellite
- Deoxyribonucleases, Type II Site-Specific
- Estrogens
- Female
- Gene Amplification
- Genes, Retinoblastoma
- Heterozygote
- Humans
- Lymphocytes
