Article
Genome scanning of human breast carcinomas using micro- and minisatellite core probes.
Genomics - 1 Jul 1993
Hovig E, Mullaart E, Børresen A L, Uitterlinden A G, Vijg J
Abstract excerpt
We have analyzed tumor and lymphocyte DNA from six breast cancer patients by one- and two-dimensional DNA fingerprinting using micro- and minisatellite core probes to estimate the extent and nature of DNA alterations in tumors. Both approaches were compared regarding sensitivity in genome analysis. We find that the number of deletions and amplifications increases linearly with the number of restriction fragments...
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