Article
The polymorphism of the immunoglobulin heavy chain switch region gene in IgA nephropathy, Henoch-Schönlein nephritis and idiopathic nephrotic syndrome.
Pediatric nephrology (Berlin, Germany) - 1 Aug 1993
Jin D K, Kohsaka T, Kobayashi N
Abstract excerpt
It is well known genetic predisposition may play an important role in the pathogenesis of renal diseases. Recently, there has been some controversy about the possible role of the polymorphism of the immunoglobulin heavy chain switch region gene. We have studied this gene by SstI restriction fragm...
Topics
- Adolescent
- Alleles
- Child
- Child, Preschool
- Genotype
- Glomerulonephritis, IGA
- Humans
- Immunoglobulin Heavy Chains
- Immunoglobulin Switch Region
- Infant
- Infant, Newborn
- Nephritis