Article
Changes in biologic phenotype of human immunodeficiency virus during treatment of patients with didanosine.
The Journal of infectious diseases - 1 May 1996
Zheng N N, McQueen P W, Hurren L, Evans L A, Law M G, Forde S, Barker S, Cooper D A, Delaney S F
Abstract excerpt
Progression to AIDS in patients harboring human immunodeficiency virus type-1 (HIV-1) isolates expressing a syncytium-inducing (SI) phenotype is faster than in those in whom the virus expresses a non-SI (NSI) phenotype. Zidovudine monotherapy does not appear to alter this outcome. To examine the role of didanosine (ddI) monotherapy in phenotype expression, HIV-1 isolates from 73 patients receiving ddI for up to...
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