A methylated CpG island 3' in the apolipoprotein-E gene does not repress its transcription.

doi:10.1093/hmg/2.6.775

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Article

A methylated CpG island 3' in the apolipoprotein-E gene does not repress its transcription.

Human molecular genetics - 1 Jun 1993

Larsen F, Solheim J, Prydz H

Abstract excerpt

CpG islands are always associated with the 5' end of housekeeping genes, covering their promoters and transcription start sites. CpG islands associated with genes of limited expression are less uniformly localized; the genes for apolipoprotein-E and -AI contain CpG islands corresponding to their...

Topics

Alleles
Amino Acid Sequence
Animals
Apolipoprotein A-I
Apolipoproteins E
Base Sequence
Genes
Genetic Variation
Humans
Methylation
Molecular Sequence Data
Organ Specificity
Papio
Polymorphism, Restriction Fragment Length
Promoter Regions, Genetic
Rats
Regulatory Sequences, Nucleic Acid
Species Specificity

Source

Open in PubMed

Identifiers

PMID: 8102571
DOI: 10.1093/hmg/2.6.775

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-8102571-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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