Article
DNA polymorphisms in linkage disequilibrium at the 3' end of the human APO AII gene: relationships with lipids, apolipoproteins and coronary heart disease.
Clinical genetics - 1 Oct 1996
Dupuy-Gorce A M, Desmarais E, Vigneron S, Buresi C, Nicaud V, Evans A, Luc G, Arveiler D, Marqués-Vidal P, Cambien F, Tiret L, Crastes de Paulet A, Roizés G
Abstract excerpt
Two investigations were undertaken to analyze the 3' region of the apolipoprotein AII (Apo AII) gene in patients with myocardial infarction (MI) and controls. Previous studies have suggested that a MspI polymorphism in this gene may be associated with hypertriglyceridaemia, high levels of HDL cho...
Topics
- Adult
- Apolipoprotein A-II
- Apolipoproteins
- DNA Mutational Analysis
- Gene Frequency
- Genetic Markers
- Genotype
- Humans
- Linkage Disequilibrium
- Lipids
- Male
- Middle Aged
- Myocardial Infarction
- Polymorphism, Genetic