Article
Nucleotide pool-sensitive selection of the transcriptional start site in vivo at the Salmonella typhimurium pyrC and pyrD promoters.
Journal of bacteriology - 1 Jul 1993
Sørensen K I, Baker K E, Kelln R A, Neuhard J
Abstract excerpt
Expression of the Salmonella typhimurium pyrC and pyrD genes is regulated in response to fluctuations in the intracellular CTP/GTP pool ratio. The repressive mechanism involves the formation of a stable secondary structure (hairpin) at the 5' ends of the transcripts that precludes translational i...
Topics
- Base Sequence
- Cytidine Triphosphate
- Deoxyribonucleotides
- Dihydroorotase
- Dihydroorotate Dehydrogenase
- Enzyme Repression
- Guanosine Triphosphate
- Molecular Sequence Data
- Mutation
- Nucleic Acid Conformation
- Oxidoreductases