Detection of a restriction fragment-length polymorphism in human endometrial carcinoma DNA with an alpha-tubulin cDNA probe.

doi:10.1006/gyno.1993.1108

Back to search

Article

Detection of a restriction fragment-length polymorphism in human endometrial carcinoma DNA with an alpha-tubulin cDNA probe.

Gynecologic oncology - 1 May 1993

Mittanck D W, Wigley W C, Li X, Alecozay A A, Nakashima R A

Abstract excerpt

We report a significant excess of heterozygotes at an alpha-tubulin locus in individuals with endometrial carcinoma. Although the heterozygous state was not specific for cancer, there was a 2.6-fold increase in heterozygote frequencies in endometrial tumors over those of normal human endometrial...

Topics

Alleles
DNA
DNA Probes
DNA, Neoplasm
Endometrial Neoplasms
Female
Humans
Polymorphism, Restriction Fragment Length
Tubulin

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.