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Article

Somatic cell mapping of the bovine prion protein gene and restriction fragment length polymorphism studies in cattle and sheep.

Animal genetics - 1 Feb 1993

Ryan A M, Womack J E

Abstract excerpt

Brains affected by the progressive neurological disease bovine spongiform encephalopathy (BSE) contain scrapie-associated fibrils and the protease-resistant isoform of prion protein. The gene encoding the normal host prion protein (PRNP) has been mapped to human chromosome 20 and mouse chromosome 2 with the hamster cDNA probe pEA974. Using this probe and a panel of bovine-rodent hybrid somatic cells, we have...

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Source

Identifiers

PMID: 8098922
DOI: 10.1111/j.1365-2052.1993.tb00914.x

Genes

PRNP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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