Article
Loss of function of the Drosophila zfh-1 gene results in abnormal development of mesodermally derived tissues.
Proceedings of the National Academy of Sciences of the United States of America - 1 May 1993
Lai Z C, Rushton E, Bate M, Rubin G M
Abstract excerpt
The Drosophila zfh-1 gene encodes an unusual protein with nine Cys2His2 type zinc-finger motifs and one homeodomain that shows a complex pattern of expression in the embryonic mesoderm and nervous system. To study the function of zfh-1, we generated loss-of-function zfh-1 mutations. Phenotypic an...
Topics
- Alleles
- Amino Acid Sequence
- Animals
- Crosses, Genetic
- DNA-Binding Proteins
- Drosophila
- Drosophila Proteins
- Embryo, Nonmammalian
- Female
- Genes, Homeobox
- Immunohistochemistry
- Male
- Mesoderm
- Molecular Sequence Data
- Muscles
- Nervous System
- Nervous System Physiological Phenomena
- Organ Specificity