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Article

Loss of function of the Drosophila zfh-1 gene results in abnormal development of mesodermally derived tissues.

Proceedings of the National Academy of Sciences of the United States of America - 1 May 1993

Lai Z C, Rushton E, Bate M, Rubin G M

Abstract excerpt

The Drosophila zfh-1 gene encodes an unusual protein with nine Cys2His2 type zinc-finger motifs and one homeodomain that shows a complex pattern of expression in the embryonic mesoderm and nervous system. To study the function of zfh-1, we generated loss-of-function zfh-1 mutations. Phenotypic analysis of zfh-1 mutant embryos reveals that the gene is not required for the initial segregation of the mesoderm or for...

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Identifiers

PMID: 8097886
DOI: 10.1073/pnas.90.9.4122
PMCID: PMC46458

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