Article
T-cell activation. V. Anti-major histocompatibility complex class I antibody-induced activation and clonal abortion in Jurkat T-leukaemic cells.
Immunology - 1 Mar 1993
Claesson M H, Dissing S, Tscherning T, Geisler C
Abstract excerpt
We have studied activation-induced changes in intracellular calcium [Ca2+]i, interleukin-2 (IL-2) secretion, and clonal abortion of the human leukaemic T-cell line Jurkat and three T-cell receptor (TcR)/CD3 receptor negative clones deficient for the TcR alpha, TcR beta and CD3 gamma chains respec...
Topics
- Antigens, Differentiation, T-Lymphocyte
- CD2 Antigens
- CD3 Complex
- Calcium
- Cell Line
- Histocompatibility Antigens Class I
- Humans
- Interleukin-2
- Leukemia, T-Cell
- Lymphocyte Activation
- Mutation
- Neoplastic Stem Cells
- Receptors, Immunologic
- T-Lymphocytes
- Transfection
- Tumor Cells, Cultured