Article
The expression pattern of the chicken homeobox-containing gene GHox-7 in developing polydactylous limb buds suggests its involvement in apical ectodermal ridge-directed outgrowth of limb mesoderm and in programmed cell death.
Differentiation; research in biological diversity - 1 Jan 1993
Coelho C N, Upholt W B, Kosher R A
Abstract excerpt
The limb buds of the polydactylous mutant embryos, talpid2 and diplopodia-5, possess expanded distal apexes surmounted by prolongated thickened apical ectodermal ridges that promote the outgrowth and formation of digits from both the anterior and posterior mesoderm of the mutant limb buds. The ch...
Topics
- Animals
- Apoptosis
- Avian Proteins
- Cell Polarity
- Chick Embryo
- DNA-Binding Proteins
- Ectoderm
- Embryonic and Fetal Development
- Extremities
- Gene Expression
- Genes, Homeobox